Wednesday, 08 May 2019 11:14

What is Frontotemporal Dementia??

Frontotemporal dementia or FTD is the 5th most common cause of dementia. It's also referred to as frontal lobe dementia and tends to start at younger ages... It often occurs between the ages of 45 and 65, but can also start as early as age 20! It's estimated that there are approximately 60,000 people living with FTD in the US. alt 2

 FTD can be challenging for doctors to diagnose. The signs and symptoms can be very different from one person to another. In the past, people have often been misdiagnosed with depression, schizophrenia or Alzheimer's disease.

FTD affects the frontal and temporal lobes of the brain. It's also known as Pick's disease. The affected areas of the brain control personality, emotions, behavior, executive functioning, and speech. At first, frontotemporal disorders leave other brain regions untouched, including those that control short-term memory.

FTD is divided into 3 categories based on the most prominent symptoms in each:

  • Behavioral variant frontotemporal dementia (bvFTD) – affects personality and behavior
  • Primary progressive aphasia (PPA) – first affects speech, then behavior
  • Progressive non-fluent aphasia – causes loss of ability to recall and speak words.

The most common signs and symptoms of frontotemporal dementia are extreme changes in behavior and personality. In the early stages of FTD, people typically have one type of symptom. As the disease progresses, more types of symptoms will appear as more parts of the brain are affected.

It's important to know that these behaviors are caused by physical damage inside the brain and aren't things the person can control or contain. Often, they aren't even aware that their behavior has changed or that it's become a problem. 

Common behavioral and personality symptoms (especially in bvFTD)

  • Changes in personality and mood – like becoming depressed, self-centered, or withdrawn
  • Avoiding socializing or being unwilling to talk
  • Repetitive or obsessive behavior
  • Lack of inhibition or lack of social tact
  • A decline in personal hygiene
  • Lack of judgment
  • Apathy – like no longer paying attention to hobbies and interests
  • Lack of awareness of thinking or behavioral changes
  • Loss of empathy and other interpersonal skills
  • Increasingly inappropriate actions like unusual verbal, physical or sexual behavior
  • Changes in eating habits, especially overeating
  • Weight gain due to overeating
  • Putting things in the mouth or trying to eat inedible objects

However, people with FTD can usually keep track of day-to-day events and understand what’s going on around them. And people with bvFTD usually keep their language skills and memory until late in the disease.

Common speech and language symptoms (especially in PPA)

  • Difficulty finding the right word or in calling objects by the correct name
  • Trouble with reading and writing
  • Losing the ability to understand or put together words in a spoken sentence
  • Speaking in a very hesitant or ungrammatical way.

Some people with FTD could have severe problems recalling and understanding words, but still, be able to speak fairly normally. But as the disease progresses, less and less language is used until the person becomes practically mute.

In later stages of FTD, people develop movement problems. Some people may develop amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease). This would include issues such as Tremors, rigid muscles, muscle spasms or weakness, poor coordination and difficulty swallowing.

Unfortunately, there isn't a single test that specifically diagnoses FTD. Doctors must try to identify certain characteristics while ruling out other possible causes, like liver or kidney disease. It can be especially difficult to diagnose in the early stages because the symptoms often overlap with those of other conditions.

Standard testing may include blood tests, MRI, CT scan, PET scan, and neuropsychological testing. Other testing may include: Blood tests to help identify other conditions that could cause similar symptoms; neuropsychological testing to check judgment and memory skills as well as to help determine the type of dementia, especially at an early stage; brain imaging to check for tumors, bleeding, or clots; magnetic resonance imaging (MRI) tests to give doctors a detailed image of the brain; computerized tomography (CT) scans to create images of the brain in layers.

Unfortunately, like other dementia's, FTD is a progressive disease with no cure. That means the symptoms will worsen over time. The speed of decline will be different for each person.

Current treatments focus on easing symptoms, but can't slow the progression. There are medications that can be used to improve the quality of life by reducing behavioral symptoms.

FTD shortens a person's life span. Each person is different, but most people with FTD live 6 to 10 years after the first symptoms are diagnosed. FTD will eventually cause a person to have difficulty with essential bodily functions like chewing, swallowing, moving around and controlling the bladder and bowels. These changes can cause serious infections in the lungs, urinary tract, and skin - leading to death.

 

 Contact us